Interactions between adenosine receptors and other membrane receptors
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چکیده
منابع مشابه
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Adenosine acts as neuromodulator in the brain, which its involvement in a wide range of brain processes and diseases has been studied, such as epilepsy, sleep, anxiety, panic disorder, Alzheimer’s disease, Parkinson’s disease and schizophrenia. Adenosine receptors have been detected: A1R, A2AR (A2AR), A2BR, and A3R. A1R and A2R inhibit cAMP production, while A2AR and A2BR stimulate cAMP product...
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متن کاملLipid-helix interactions in membrane receptors.
The integration of the transmembrane (TM) proteins in the lipid bilayer depend on lipid-protein interactions. The few crystal structures known for multiple membrane spanning proteins suggest a basic form composed of bundles of a-helices that pack together. In the membrane helix-helix and helix-lipid interaction define the helix arrangement in the folded receptor. Thus, the lipid-protein interac...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1990
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)32899-9